There’s something magical about turkey tetrazzini that brings the warmth of home right to your dinner table. Imagine a creamy, dreamy pasta dish loaded with tender turkey, crunchy vegetables, and a sprinkle of cheese that melts into pure deliciousness. Each bite is a cozy hug for your taste buds, making it hard to resist going back for seconds—or thirds.
This delightful dish holds a special place in my heart. I remember the first time I made turkey tetrazzini for my family; they devoured it faster than I could say “leftovers.” Whether it’s game night or a holiday gathering, this dish shines in any setting, promising an unforgettable flavor experience that leaves everyone smiling.
Why You'll Love This Recipe
- Turkey tetrazzini is easy to prepare and perfect for busy weeknights
- The rich flavors and creamy texture create a comforting meal that pleases everyone
- Its visual appeal with colorful veggies makes it irresistible on the table
- Versatile enough to use leftover turkey or chicken, this dish adapts well to your pantry staples
The first time I served turkey tetrazzini, my friends declared me the reigning queen of comfort food. Their satisfied faces were all the validation I needed.

Essential Ingredients
Here’s what you’ll need to make this delicious dish:
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Cooked Turkey: Use leftover turkey from Thanksgiving or rotisserie chicken; both work wonderfully here.
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Pasta: I prefer wide egg noodles for their ability to hold onto the sauce beautifully.
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Cream of Mushroom Soup: This adds creaminess and depth; opt for low-fat if you want a lighter version.
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Milk: Use whole milk for richness; it enhances the creaminess of the sauce.
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Shredded Cheese: A combination of mozzarella and Parmesan gives that gooey, golden topping everyone loves.
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Mixed Vegetables: Fresh or frozen peas and mushrooms add color and nutrition; they’re great for sneaking in some greens.
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Onion and Garlic: These two are essential for flavor; sauté them until fragrant to kick-start the dish.
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Breadcrumbs.: Topping with breadcrumbs creates a crunchy contrast to the creamy pasta beneath.
The full ingredients list, including measurements, is provided in the recipe card directly below.
Let’s Make it Together
Preheat Your Oven: Preheat your oven to 350°F (175°C). This ensures your turkey tetrazzini bakes evenly and gets that golden crust you crave.
Cook Your Pasta: Boil water in a large pot with a pinch of salt. Add the egg noodles and cook until al dente—about 6-8 minutes will do. Drain and set aside.
Sauté Aromatics: In a skillet over medium heat, melt butter and add chopped onion and minced garlic. Sauté until translucent and aromatic—about 3-4 minutes.
Combine Ingredients: In a large bowl, mix cooked pasta, shredded turkey, cream of mushroom soup, milk, sautéed onions, mixed vegetables, and half of your cheese. Stir until everything is well coated.
Transfer to Baking Dish: Pour the mixture into a greased 9×13-inch baking dish. Spread evenly then sprinkle remaining cheese on top along with breadcrumbs for crunch.
Bake: Place in the preheated oven and bake for about 25-30 minutes until bubbly and golden brown on top. Let it cool slightly before serving—it’ll be tempting but trust me!
Enjoy Your Creation: Serve warm with a sprinkle of fresh parsley or additional cheese if desired. Watch as your family digs in happily!
With each step completed, you’ve not only made turkey tetrazzini but created memories that will last long beyond dinner time! Enjoy every moment as you savor this delectable dish together!
You Must Know
- Turkey Tetrazzini is comfort food at its finest, combining creamy texture with savory flavor
- It’s perfect for using leftover turkey and can be easily customized to suit your taste
- The aroma while baking will make everyone flock to the kitchen
Perfecting the Cooking Process
Start by cooking the pasta until al dente, then sauté vegetables while preparing the sauce for efficiency. This sequence ensures everything melds perfectly without overcooking any ingredients.

Add Your Touch
Feel free to substitute chicken for turkey or add veggies like spinach or bell peppers for extra nutrients. Experiment with different cheeses or spices to make the dish uniquely yours.
Storing & Reheating
Store leftovers in an airtight container in the fridge for up to four days. Reheat in the oven at 350°F until warmed through, about 20 minutes, for best texture.
Chef's Helpful Tips
- To achieve a creamy sauce, avoid boiling it too long; simmer gently instead
- Adding a sprinkle of Parmesan on top before baking creates a lovely crust
- Remember to taste as you go; seasoning makes all the difference!
Sharing this dish always brings nostalgia, as I recall making it with my grandmother every Thanksgiving. Her secret ingredient? A dash of love (and garlic)!

FAQ
Can I use chicken instead of turkey in turkey tetrazzini?
Absolutely! Chicken works just as well and is equally delicious in this recipe.
What type of pasta is best for turkey tetrazzini?
Fettuccine or penne are ideal choices; they hold onto the sauce nicely.
How can I make my turkey tetrazzini healthier?
Try adding more vegetables or using whole wheat pasta for added fiber and nutrients.
Turkey Tetrazzini
Turkey Tetrazzini is a comforting pasta dish that combines tender turkey, creamy sauce, and vibrant vegetables for a satisfying meal. Perfect for using leftovers, this recipe is quick to prepare and ideal for busy weeknights or gatherings. Each bite delivers warmth and nostalgia, ensuring it becomes a family favorite.
- Prep Time: 15 minutes
- Cook Time: 30 minutes
- Total Time: 45 minutes
- Yield: Serves 8
- Category: Main
- Method: Baking
- Cuisine: American
Ingredients
- 3 cups cooked turkey (shredded)
- 8 oz wide egg noodles
- 1 can (10.5 oz) cream of mushroom soup
- 1 cup whole milk
- 1 cup shredded mozzarella cheese
- 1/2 cup grated Parmesan cheese
- 1 cup mixed vegetables (peas and mushrooms)
- 1 small onion (chopped)
- 2 cloves garlic (minced)
- 1/2 cup breadcrumbs
- 2 tbsp butter
Instructions
- Preheat oven to 350°F (175°C).
- Cook egg noodles in salted boiling water until al dente (6-8 minutes). Drain and set aside.
- In a skillet, melt butter over medium heat; sauté onion and garlic until translucent (3-4 minutes).
- In a large bowl, combine noodles, turkey, cream of mushroom soup, milk, sautéed onions, mixed vegetables, and half the mozzarella cheese.
- Transfer to a greased 9×13-inch baking dish; top with remaining cheese and breadcrumbs.
- Bake for 25-30 minutes until bubbly and golden brown. Let cool slightly before serving.
Nutrition
- Serving Size: 1 serving
- Calories: 410
- Sugar: 3g
- Sodium: 650mg
- Fat: 18g
- Saturated Fat: 10g
- Unsaturated Fat: 7g
- Trans Fat: 0g
- Carbohydrates: 40g
- Fiber: 3g
- Protein: 24g
- Cholesterol: 75mg





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